Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: an explorative study
نویسندگان
چکیده
Proximity extension assay proves feasible for multiplex analysis of proteins in bronchoalveolar lavage. Small exploratory study found multiple inflammatory that differed between patients with sarcoidosis and idiopathic pulmonary fibrosis.https://bit.ly/3nW14nF
منابع مشابه
The role of Bronchoalveolar lavage in Interstitial Lung Diseases.
Interstitial Lung Diseases (ILD) are a group of diseases characterized by bilateral involvement of lung parenchyma, acutely or chronically, which have different degrees of fibrosis and tissue inflammation and which occur in immunocompetent hosts, without infection or neoplasia. Bronchoalveolar lavage (BAL) is a useful diagnostic tool for ILD. The cellular profile obtained by BAL, in association...
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INTRODUCTION Previous studies have suggested that hepatocyte growth factor (HGF) inhibits lung fibrosis as an antagonist of transforming growth factor β (TGF‑β). OBJECTIVES We assessed HGF expression levels in the lower airways of patients with selected interstitial lung diseases. PATIENTS AND METHODS HGF levels were examined by an enzyme‑linked immunosorbent assay in bronchoalveolar lav...
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1Department of Medicine, Rheumatology Unit, University of Padova, Padova, Italy: 2Department of Medicine, Clinical Immunology Branch, University of Padova, Padova, Italy; 3Department of Medical Diagnostic Sciences and Special Therapies, Radiology Section, University of Padova, Padova, Italy; 4Department of Biomedicine, Division of Rheumatology, University of Florence, Florence, Italy. Paolo Sfr...
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Occupational lung diseases (OLDs) are related to the exposure and inhalation of organic, inorganic, and synthetic particles, fumes, gases, or infectious agents. From the long list of OLDs this article focuses the discussion on bronchoalveolar lavage (BAL) in parenchymal immunoinflammatory conditions, such as hypersensitivity pneumonitis (HP) and pneumoconiosis. Several antigens may cause HP, in...
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ژورنال
عنوان ژورنال: ERJ Open Research
سال: 2021
ISSN: ['2312-0541']
DOI: https://doi.org/10.1183/23120541.00489-2020